What will it take

Implementing CER: what will it take?

BACKGROUND Comparative effectiveness research (CER) is undeniably changing how drugs are developed, launched, priced, and reimbursed in the United States. But most organizations are still evaluating what CER can do for them and how and when they can utilize the data. A roundtable of stakeholders, including formulary decision makers, evaluated CER's possible effects on managed care organizations...

What Will It Take to Cure HIV?

Investigational strategies to attempt HIV cure or remission include very early initiation of antiretroviral therapy to limit the latent HIV reservoir and preinfection vaccination. In the setting of viral suppression, strategies include reactivation of latently infected cells (eg, through "shock" therapy with histone deacetylase inhibitors or other agents); use of broadly neutralizing antibodies...

What will it take to stop obesity?

O besity has reached epidemic proportions in industrialized countries like the United States, resulting in increased morbidity and mortality, decreased productivity and function, and soaring health care costs. In the United States, the explosion of fast food restaurants, with their high-fat, supersized portions containing little nutritive value, is considered a major contributor to obesity. In ...

Effective Aid by 2010? What It Will Take

Routine integration of palliative care: what will it take?

alliative care has substantial benefits for patients with advanced disease, including improved symptom relief, quality of life, and communication around health care goals.1 These benefits extend to the patient’s family,2 improving caregiver quality of life and bereavement outcomes.3 Palliative care is also associated with cost savings with reduced hospitalisations and emergency department prese...